Metformin-induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

The proliferation and migration of vascular smooth muscle cells are significant in the development and progression of atherosclerosis and plaque rupture. Metformin is a widely used antidiabetic drug, which has been reported to inhibit cell growth and migration. The antiproliferative and antimigrator...

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Detalles Bibliográficos
Autores principales: Hao, Biao, Xiao, Yan, Song, Fang, Long, Xiangshu, Huang, Jing, Tian, Maobo, Deng, Shiyan, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819901/
https://www.ncbi.nlm.nih.gov/pubmed/29286156
http://dx.doi.org/10.3892/ijmm.2017.3346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819901/
https://www.ncbi.nlm.nih.gov/pubmed/29286156
http://dx.doi.org/10.3892/ijmm.2017.3346

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