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Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway

Renal tubulointerstitial inflammation has an important role in fibrosis, which is the main pathogenetic alteration associated with chronic kidney disease (CKD). The left-right determination factor 1 (Lefty-1) gene pleiotropically and biologically regulates transforming growth factor, mitogen-activat...

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Detalles Bibliográficos
Autores principales: Zhang, Lijun, Xu, Changgeng, Hu, Wei, Wu, Pin, Qin, Cong, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819905/
https://www.ncbi.nlm.nih.gov/pubmed/29286065
http://dx.doi.org/10.3892/ijmm.2017.3327