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shRNA-induced silencing of Ras-related C3 botulinum toxin substrate 1 inhibits the proliferation of colon cancer cells through upregulation of BAD and downregulation of cyclin D1

Ras-related C3 botulinum toxin substrate 1 (RAC1) is a member of the Rho family of small GTPases. Recent studies have reported that RAC1 serves an important role in colon cancer cell proliferation. The present study aimed to investigate the effects of RAC1 knockdown on cell proliferation, cell cycle...

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Detalles Bibliográficos
Autores principales: Huang, You-Sheng, Jie, Na, Zhang, Yi-Xin, Zou, Ke-Jian, Weng, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819921/
https://www.ncbi.nlm.nih.gov/pubmed/29286138
http://dx.doi.org/10.3892/ijmm.2017.3345