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NPPB modulates apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling

When treating glaucoma, excessive scar tissue reactions reduce the postoperative survival rate of the filtering bleb. Accumulating evidence has demonstrated that the proliferation, migration and extracellular matrix (ECM) synthesis of fibroblasts are important molecular mechanisms underlying scar fo...

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Detalles Bibliográficos
Autores principales: Sun, Lixia, Dong, Yaru, Zhao, Jing, Yin, Yuan, Tong, Bainan, Zheng, Yajuan, Xin, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819927/
https://www.ncbi.nlm.nih.gov/pubmed/29286070
http://dx.doi.org/10.3892/ijmm.2017.3323