Translational control of ERK signaling through miRNA/4EHP-directed silencing

MicroRNAs (miRNAs) exert a broad influence over gene expression by directing effector activities that impinge on translation and stability of mRNAs. We recently discovered that the cap-binding protein 4EHP is a key component of the mammalian miRNA-Induced Silencing Complex (miRISC), which mediates g...

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Detalles Bibliográficos
Autores principales: Jafarnejad, Seyed Mehdi, Chapat, Clément, Matta-Camacho, Edna, Gelbart, Idit Anna, Hesketh, Geoffrey G, Arguello, Meztli, Garzia, Aitor, Kim, Sung-Hoon, Attig, Jan, Shapiro, Maayan, Morita, Masahiro, Khoutorsky, Arkady, Alain, Tommy, Gkogkas, Christos, G, Stern-Ginossar, Noam, Tuschl, Thomas, Gingras, Anne-Claude, Duchaine, Thomas F, Sonenberg, Nahum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819943/
https://www.ncbi.nlm.nih.gov/pubmed/29412140
http://dx.doi.org/10.7554/eLife.35034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819943/
https://www.ncbi.nlm.nih.gov/pubmed/29412140
http://dx.doi.org/10.7554/eLife.35034

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