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Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

Photoactivation ('uncaging’) is a powerful approach for releasing bioactive small-molecules in living cells. Current uncaging methods are limited by the random distribution of caged molecules within cells. We have developed a mitochondria-specific photoactivation method, which permitted us to r...

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Detalles Bibliográficos
Autores principales: Feng, Suihan, Harayama, Takeshi, Montessuit, Sylvie, David, Fabrice PA, Winssinger, Nicolas, Martinou, Jean-Claude, Riezman, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819948/
https://www.ncbi.nlm.nih.gov/pubmed/29376826
http://dx.doi.org/10.7554/eLife.34555