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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions

Molecular recognition is integral to biological function and frequently involves preferred binding of a molecule to one of several exchanging ligand conformations in solution. In such a process the bound structure can be selected from the ensemble of interconverting ligands a priori (conformational...

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Detalles Bibliográficos
Autores principales: Sekhar, Ashok, Velyvis, Algirdas, Zoltsman, Guy, Rosenzweig, Rina, Bouvignies, Guillaume, Kay, Lewis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819949/
https://www.ncbi.nlm.nih.gov/pubmed/29460778
http://dx.doi.org/10.7554/eLife.32764