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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions
Molecular recognition is integral to biological function and frequently involves preferred binding of a molecule to one of several exchanging ligand conformations in solution. In such a process the bound structure can be selected from the ensemble of interconverting ligands a priori (conformational...
Autores principales: | Sekhar, Ashok, Velyvis, Algirdas, Zoltsman, Guy, Rosenzweig, Rina, Bouvignies, Guillaume, Kay, Lewis E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819949/ https://www.ncbi.nlm.nih.gov/pubmed/29460778 http://dx.doi.org/10.7554/eLife.32764 |
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