Progression process and safety assessment adaptation of endometrial lesions in ENU-induced 2-stage uterine carcinogenicity in a Tg-rasH2 mouse model

Although acotiamide hydrochloride hydrate (acotiamide-HH) has not been reported to have genotoxic findings in any of the genotoxicity studies or treatment-related toxicological findings in reproductive and developmental studies, suspicious uterine tumorigenesis was observed in the results of a long-...

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Detalles Bibliográficos
Autores principales: Kuroda, Hiroyuki, Kinomoto, Toshiko, Ogawa, Shuji, Kawabe, Mayumi, Suguro, Mayuko, Naraoka, Hitoshi, Takamatsu, Kazuhiko, Oishi, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820101/
https://www.ncbi.nlm.nih.gov/pubmed/29479138
http://dx.doi.org/10.1293/tox.2017-0035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820101/
https://www.ncbi.nlm.nih.gov/pubmed/29479138
http://dx.doi.org/10.1293/tox.2017-0035

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