Compensatory increases in tear volume and mucin levels associated with meibomian gland dysfunction caused by stearoyl-CoA desaturase-1 deficiency

The stearoyl-CoA desaturase (SCD) family of enzymes catalyzes monounsaturated fatty acid synthesis by inserting a cis double bond at the Δ9 position of saturated fatty acids. Disruption of these enzymes has been reported to induce a severe dry skin phenotype. Since lipid abnormalities in the meibomi...

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Detalles Bibliográficos
Autores principales: Inaba, Takaaki, Tanaka, Yasuhisa, Tamaki, Shusaku, Ito, Tomotaka, Ntambi, James M., Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820245/
https://www.ncbi.nlm.nih.gov/pubmed/29463801
http://dx.doi.org/10.1038/s41598-018-21542-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820245/
https://www.ncbi.nlm.nih.gov/pubmed/29463801
http://dx.doi.org/10.1038/s41598-018-21542-3

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