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Compensatory increases in tear volume and mucin levels associated with meibomian gland dysfunction caused by stearoyl-CoA desaturase-1 deficiency
The stearoyl-CoA desaturase (SCD) family of enzymes catalyzes monounsaturated fatty acid synthesis by inserting a cis double bond at the Δ9 position of saturated fatty acids. Disruption of these enzymes has been reported to induce a severe dry skin phenotype. Since lipid abnormalities in the meibomi...
Autores principales: | Inaba, Takaaki, Tanaka, Yasuhisa, Tamaki, Shusaku, Ito, Tomotaka, Ntambi, James M., Tsubota, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820245/ https://www.ncbi.nlm.nih.gov/pubmed/29463801 http://dx.doi.org/10.1038/s41598-018-21542-3 |
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