Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

Interleukin (IL)-33 is an IL-1 family alarmin released from damaged epithelial and endothelial barriers to elicit immune responses and allergic inflammation via its receptor ST2. Serine proteases released from neutrophils, mast cells and cytotoxic lymphocytes have been proposed to process the N-term...

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Detalles Bibliográficos
Autores principales: Scott, Ian C., Majithiya, Jayesh B., Sanden, Caroline, Thornton, Peter, Sanders, Philip N., Moore, Tom, Guscott, Molly, Corkill, Dominic J., Erjefält, Jonas S., Cohen, E. Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820248/
https://www.ncbi.nlm.nih.gov/pubmed/29463838
http://dx.doi.org/10.1038/s41598-018-21589-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820248/
https://www.ncbi.nlm.nih.gov/pubmed/29463838
http://dx.doi.org/10.1038/s41598-018-21589-2

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