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Changed frontal pole gene expression suggest altered interplay between neurotransmitter, developmental, and inflammatory pathways in schizophrenia

Schizophrenia (Sz) probably occurs after genetically susceptible individuals encounter a deleterious environmental factor that triggers epigenetic mechanisms to change CNS gene expression. To determine if omnibus changes in CNS gene expression are present in Sz, we compared mRNA levels in the fronta...

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Detalles Bibliográficos
Autores principales: Scarr, Elizabeth, Udawela, Madhara, Dean, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820249/
https://www.ncbi.nlm.nih.gov/pubmed/29463818
http://dx.doi.org/10.1038/s41537-018-0044-x