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Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease
Polycystic kidney disease (PKD) is a genetic disorder characterized by fluid-filled cysts in the kidney and liver that ultimately leads to end-stage renal disease. Currently there is no globally approved therapy for PKD. The Notch signaling pathway regulates cellular processes such as proliferation...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820265/ https://www.ncbi.nlm.nih.gov/pubmed/29463793 http://dx.doi.org/10.1038/s41598-018-21132-3 |