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Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease

Polycystic kidney disease (PKD) is a genetic disorder characterized by fluid-filled cysts in the kidney and liver that ultimately leads to end-stage renal disease. Currently there is no globally approved therapy for PKD. The Notch signaling pathway regulates cellular processes such as proliferation...

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Detalles Bibliográficos
Autores principales:	Idowu, Jessica, Home, Trisha, Patel, Nisha, Magenheimer, Brenda, Tran, Pamela V., Maser, Robin L., Ward, Christopher J., Calvet, James P., Wallace, Darren P., Sharma, Madhulika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820265/ https://www.ncbi.nlm.nih.gov/pubmed/29463793 http://dx.doi.org/10.1038/s41598-018-21132-3

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