Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice

Niemann-Pick disease Type C1 (NPC1) is a rare hereditary neurodegenerative disease. NPC1-patients suffer, amongst others, from ataxia, based on a loss of cerebellar Purkinje cells (PCs). Impaired expression/function of excitatory amino acid transporters (EAATs) are suspected of contributing to PC-de...

Descripción completa

Detalles Bibliográficos
Autores principales: Rabenstein, Michael, Peter, Franziska, Rolfs, Arndt, Frech, Moritz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820268/
https://www.ncbi.nlm.nih.gov/pubmed/29463856
http://dx.doi.org/10.1038/s41598-018-21805-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820268/
https://www.ncbi.nlm.nih.gov/pubmed/29463856
http://dx.doi.org/10.1038/s41598-018-21805-z

Ejemplares similares