Autoantibodies against the Immunoglobulin-Binding Region of Ro52 Link its Autoantigenicity with Pathogen Neutralization

Ro52/TRIM21 plays a key role in antibody-dependent pathogen neutralization and is a major autoantigen in systemic lupus erythematosus, Sjögren’s syndrome (SS), and other autoimmune diseases. Here we evaluated immunoreactivity against Ro52-related molecules in SS and healthy volunteers. Although most...

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Detalles Bibliográficos
Autores principales: Burbelo, Peter D., Teos, Leyla Y., Herche, Jesse L., Iadarola, Michael J., Alevizos, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820281/
https://www.ncbi.nlm.nih.gov/pubmed/29463848
http://dx.doi.org/10.1038/s41598-018-21522-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820281/
https://www.ncbi.nlm.nih.gov/pubmed/29463848
http://dx.doi.org/10.1038/s41598-018-21522-7

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