True gene-targeting events by CRISPR/Cas-induced DSB repair of the PPO locus with an ectopically integrated repair template

In recent years, several tools have become available for improved gene-targeting (GT) in plants. DNA breaks at specific sites activate local DNA repair and recombination, including recombination with ectopic sequences leading to GT. Large-scale transformation with the repair template can be avoided...

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Detalles Bibliográficos
Autores principales: de Pater, Sylvia, Klemann, Bart J. P. M., Hooykaas, Paul J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820285/
https://www.ncbi.nlm.nih.gov/pubmed/29463822
http://dx.doi.org/10.1038/s41598-018-21697-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820285/
https://www.ncbi.nlm.nih.gov/pubmed/29463822
http://dx.doi.org/10.1038/s41598-018-21697-z

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