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The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly

The PICALM rs541458 T allele has been recognized as a risk factor for late-onset Alzheimer’s disease, and age might modulate the effects that genetic factors have on cognitive functions and brain. Thus, the current study intended to examine whether the effects of rs541458 on cognitive functions, bra...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Dai, Xiangwei, Zhang, Junying, Li, Xin, Chen, Yaojing, Ma, Chao, Chen, Kewei, Peng, Dantao, Zhang, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820373/
https://www.ncbi.nlm.nih.gov/pubmed/28116548
http://dx.doi.org/10.1007/s12035-016-0358-5