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Distribution of Alox15 in the Rat Brain and Its Role in Prefrontal Cortical Resolvin D1 Formation and Spatial Working Memory

Docosahexaenoic acid (DHA) is enriched in membrane phospholipids of the central nervous system (CNS) and has a role in aging and neuropsychiatric disorders. DHA is metabolized by the enzyme Alox15 to 17S-hydroxy-DHA, which is then converted to 7S-hydroperoxy,17S-hydroxy-DHA by a 5-lipoxygenase, and...

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Detalles Bibliográficos
Autores principales: Shalini, Suku-Maran, Ho, Christabel Fung-Yih, Ng, Yee-Kong, Tong, Jie-Xin, Ong, Eng-Shi, Herr, Deron R., Dawe, Gavin S., Ong, Wei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820376/
https://www.ncbi.nlm.nih.gov/pubmed/28181190
http://dx.doi.org/10.1007/s12035-017-0413-x