Evaluation of Treatment Effect with Paired Failure Times in a Single-Arm Phase II Trial in Oncology

In early phase clinical trials of cytotoxic drugs in oncology, the efficacy is typically evaluated based on the tumor shrinkage. However, this criterion is not always appropriate for more recent cytostatic agents, and alternative endpoints have been proposed. The growth modulation index (GMI), defin...

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Detalles Bibliográficos
Autores principales: Texier, Matthieu, Rotolo, Federico, Ducreux, Michel, Bouché, Olivier, Pignon, Jean-Pierre, Michiels, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820554/
https://www.ncbi.nlm.nih.gov/pubmed/29568321
http://dx.doi.org/10.1155/2018/1672176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820554/
https://www.ncbi.nlm.nih.gov/pubmed/29568321
http://dx.doi.org/10.1155/2018/1672176

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