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Nobiletin Inhibits Hepatic Lipogenesis via Activation of AMP-Activated Protein Kinase

We aimed to investigate the effects of nobiletin on hepatic lipogenesis in high glucose-induced lipid accumulation in HepG2 cells. Nobiletin, a citrus polymethoxyflavonoid with six methoxy groups, is present abundantly in the peels of citrus fruits. HepG2 cells were incubated in Dulbecco's modi...

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Detalles Bibliográficos
Autores principales: Yuk, Taewon, Kim, Younghwa, Yang, Jinwoo, Sung, Jeehye, Jeong, Heon Sang, Lee, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820556/
https://www.ncbi.nlm.nih.gov/pubmed/29552085
http://dx.doi.org/10.1155/2018/7420265