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Stromal Cell-Derived Factor-1α Alleviates Calcium-Sensing Receptor Activation-Mediated Ischemia/Reperfusion Injury by Inhibiting Caspase-3/Caspase-9-Induced Cell Apoptosis in Rat Free Flaps

Surgical flaps are frequently affected by ischemia/reperfusion (I/R) injury. Calcium-sensing receptor (CaSR) and stromal cell-derived factor-1α (SDF-1α) are closely associated with myocardial I/R injury. This study was performed to evaluate the feasibility of applying SDF-1α to counteract CaSR activ...

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Detalles Bibliográficos
Autores principales: Song, Li, Gao, Li-Na, Wang, Jun, Thapa, Swosti, Li, Yong, Zhong, Xiao-Bo, Zhao, Hong-Wei, Xiang, Xue-Rong, Zhang, Fu-Gui, Ji, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820583/
https://www.ncbi.nlm.nih.gov/pubmed/29568770
http://dx.doi.org/10.1155/2018/8945850