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Orthogonality and Burdens of Heterologous AND Gate Gene Circuits in E. coli
[Image: see text] Synthetic biology approaches commonly introduce heterologous gene networks into a host to predictably program cells, with the expectation of the synthetic network being orthogonal to the host background. However, introduced circuits may interfere with the host’s physiology, either...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820654/ https://www.ncbi.nlm.nih.gov/pubmed/29240998 http://dx.doi.org/10.1021/acssynbio.7b00328 |