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Toward an integrated map of genetic interactions in cancer cells

Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic backgroun...

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Detalles Bibliográficos
Autores principales: Rauscher, Benedikt, Heigwer, Florian, Henkel, Luisa, Hielscher, Thomas, Voloshanenko, Oksana, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820685/
https://www.ncbi.nlm.nih.gov/pubmed/29467179
http://dx.doi.org/10.15252/msb.20177656