Regulated Release of Cryptococcal Polysaccharide Drives Virulence and Suppresses Immune Cell Infiltration into the Central Nervous System

Cryptococcus neoformans is a common environmental yeast and opportunistic pathogen responsible for 15% of AIDS-related deaths worldwide. Mortality primarily results from meningoencephalitis, which occurs when fungal cells disseminate to the brain from the initial pulmonary infection site. A key C. n...

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Detalles Bibliográficos
Autores principales: Denham, Steven T., Verma, Surbhi, Reynolds, Raymond C., Worne, Colleen L., Daugherty, Joshua M., Lane, Thomas E., Brown, Jessica C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Molecular Pathogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820953/
https://www.ncbi.nlm.nih.gov/pubmed/29203547
http://dx.doi.org/10.1128/IAI.00662-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820953/
https://www.ncbi.nlm.nih.gov/pubmed/29203547
http://dx.doi.org/10.1128/IAI.00662-17

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