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The role of TGF-β/SMAD4 signaling in cancer

Transforming growth factor β (TGF-β) signaling pathway plays important roles in many biological processes, including cell growth, differentiation, apoptosis, migration, as well as cancer initiation and progression. SMAD4, which serves as the central mediator of TGF-β signaling, is specifically inact...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Mishra, Lopa, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821033/
https://www.ncbi.nlm.nih.gov/pubmed/29483830
http://dx.doi.org/10.7150/ijbs.23230