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MicroRNA-21-5p mediates TGF-β-regulated fibrogenic activation of spinal fibroblasts and the formation of fibrotic scars after spinal cord injury

Little regeneration of transected axons occurs after the damage caused by traumatic spinal cord injury (SCI), and unidirectional and irreversible fibrotic scars are thought to be the main chemical and physical obstacle for axonal regrowth in SCI pathology. We previously demonstrated that microRNA (m...

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Detalles Bibliográficos
Autores principales: Wang, Wenzhao, Liu, Ronghan, Su, Yanlin, Li, Hongfei, Xie, Wei, Ning, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821039/
https://www.ncbi.nlm.nih.gov/pubmed/29483836
http://dx.doi.org/10.7150/ijbs.24074