N-glycosylation of Viral E Protein Is the Determinant for Vector Midgut Invasion by Flaviviruses

Transmission of flaviviruses by hematophagous insects such as mosquitoes requires acquisition of the virus during blood feeding on the host, with midgut as the primary infection site. Here, we report that N-glycosylation of the E protein, which is conserved among most flaviviruses, is critical for t...

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Detalles Bibliográficos
Autores principales: Wen, Dan, Li, Suhua, Dong, Fangfang, Zhang, Yanan, Lin, Yongfang, Wang, Jumei, Zou, Zhen, Zheng, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821097/
https://www.ncbi.nlm.nih.gov/pubmed/29463651
http://dx.doi.org/10.1128/mBio.00046-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821097/
https://www.ncbi.nlm.nih.gov/pubmed/29463651
http://dx.doi.org/10.1128/mBio.00046-18

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