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N-glycosylation of Viral E Protein Is the Determinant for Vector Midgut Invasion by Flaviviruses
Transmission of flaviviruses by hematophagous insects such as mosquitoes requires acquisition of the virus during blood feeding on the host, with midgut as the primary infection site. Here, we report that N-glycosylation of the E protein, which is conserved among most flaviviruses, is critical for t...
Autores principales: | Wen, Dan, Li, Suhua, Dong, Fangfang, Zhang, Yanan, Lin, Yongfang, Wang, Jumei, Zou, Zhen, Zheng, Aihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821097/ https://www.ncbi.nlm.nih.gov/pubmed/29463651 http://dx.doi.org/10.1128/mBio.00046-18 |
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