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PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

T cell non-Hodgkin lymphomas (T-NHLs) represent a heterogeneous group of highly aggressive malignancies with poor clinical outcomes1. T-NHLs originate from peripheral T lymphocytes and are frequently characterized by genetic gain-of-function variants in T cell antigen receptor (TCR) signalling molec...

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Detalles Bibliográficos
Autores principales: Wartewig, Tim, Kurgyis, Zsuzsanna, Keppler, Selina, Pechloff, Konstanze, Hameister, Erik, Öllinger, Rupert, Maresch, Roman, Buch, Thorsten, Steiger, Katja, Winter, Christof, Rad, Roland, Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821214/
https://www.ncbi.nlm.nih.gov/pubmed/29143824
http://dx.doi.org/10.1038/nature24649