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PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
T cell non-Hodgkin lymphomas (T-NHLs) represent a heterogeneous group of highly aggressive malignancies with poor clinical outcomes1. T-NHLs originate from peripheral T lymphocytes and are frequently characterized by genetic gain-of-function variants in T cell antigen receptor (TCR) signalling molec...
Autores principales: | Wartewig, Tim, Kurgyis, Zsuzsanna, Keppler, Selina, Pechloff, Konstanze, Hameister, Erik, Öllinger, Rupert, Maresch, Roman, Buch, Thorsten, Steiger, Katja, Winter, Christof, Rad, Roland, Ruland, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821214/ https://www.ncbi.nlm.nih.gov/pubmed/29143824 http://dx.doi.org/10.1038/nature24649 |
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