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CDK activity provides temporal and quantitative cues for organizing genome duplication

In eukaryotes, the spatial and temporal organization of genome duplication gives rise to distinctive profiles of replication origin usage along the chromosomes. While it has become increasingly clear that these programs are important for cellular physiology, the mechanisms by which they are determin...

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Detalles Bibliográficos
Autores principales: Perrot, Anthony, Millington, Christopher Lee, Gómez-Escoda, Blanca, Schausi-Tiffoche, Diane, Wu, Pei-Yun Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821308/
https://www.ncbi.nlm.nih.gov/pubmed/29466359
http://dx.doi.org/10.1371/journal.pgen.1007214