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Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology

Substantial evidence has accumulated linking epigenome change to alterations in stem cell function during postnatal development and aging. Yet much remains to be learned about causal relationships, and large gaps remain in our understanding of epigenome-transcriptome interactions. Here we investigat...

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Detalles Bibliográficos
Autores principales: Howard, Bruce H., Hirai, Tazuko H., Russanova, Valya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821309/
https://www.ncbi.nlm.nih.gov/pubmed/29466355
http://dx.doi.org/10.1371/journal.pone.0191033