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Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload
AIMS: In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821345/ https://www.ncbi.nlm.nih.gov/pubmed/29466442 http://dx.doi.org/10.1371/journal.pone.0192322 |