Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload

AIMS: In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is...

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Detalles Bibliográficos
Autores principales: Schirmer, Ilona, Bualeong, Tippaporn, Budde, Heidi, Cimiotti, Diana, Appukuttan, Avinash, Klein, Nicole, Steinwascher, Philip, Reusch, Peter, Mügge, Andreas, Meyer, Rainer, Ladilov, Yury, Jaquet, Kornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821345/
https://www.ncbi.nlm.nih.gov/pubmed/29466442
http://dx.doi.org/10.1371/journal.pone.0192322

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