Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility

Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated. We hypothesized that lack of MR in EC may be protective in renal vas...

Descripción completa

Detalles Bibliográficos
Autores principales: Laursen, Sidsel B., Finsen, Stine, Marcussen, Niels, Quaggin, Susan E., Hansen, Pernille B. L., Dimke, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821352/
https://www.ncbi.nlm.nih.gov/pubmed/29466427
http://dx.doi.org/10.1371/journal.pone.0193032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821352/
https://www.ncbi.nlm.nih.gov/pubmed/29466427
http://dx.doi.org/10.1371/journal.pone.0193032

Ejemplares similares