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Genetic compensation triggered by actin mutation prevents the muscle damage caused by loss of actin protein
The lack of a mutant phenotype in homozygous mutant individuals’ due to compensatory gene expression triggered upstream of protein function has been identified as genetic compensation. Whilst this intriguing process has been recognized in zebrafish, the presence of homozygous loss of function mutati...
Autores principales: | Sztal, Tamar E., McKaige, Emily A., Williams, Caitlin, Ruparelia, Avnika A., Bryson-Richardson, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821405/ https://www.ncbi.nlm.nih.gov/pubmed/29420541 http://dx.doi.org/10.1371/journal.pgen.1007212 |
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