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Tumor initiating cells induce Cxcr4-mediated infiltration of pro-tumoral macrophages into the brain

It is now clear that microglia and macrophages are present in brain tumors, but whether or how they affect initiation and development of tumors is not known. Exploiting the advantages of the zebrafish (Danio rerio) model, we showed that macrophages and microglia respond immediately upon oncogene act...

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Detalles Bibliográficos
Autores principales: Chia, Kelda, Mazzolini, Julie, Mione, Marina, Sieger, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821457/
https://www.ncbi.nlm.nih.gov/pubmed/29465400
http://dx.doi.org/10.7554/eLife.31918