Dissection of affinity captured LINE-1 macromolecular complexes

Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes. L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs). These RNPs interact with diverse host proteins, some repressive and others required for the L1 lifecycle. Using dif...

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Detalles Bibliográficos
Autores principales: Taylor, Martin S, Altukhov, Ilya, Molloy, Kelly R, Mita, Paolo, Jiang, Hua, Adney, Emily M, Wudzinska, Aleksandra, Badri, Sana, Ischenko, Dmitry, Eng, George, Burns, Kathleen H, Fenyö, David, Chait, Brian T, Alexeev, Dmitry, Rout, Michael P, Boeke, Jef D, LaCava, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821459/
https://www.ncbi.nlm.nih.gov/pubmed/29309035
http://dx.doi.org/10.7554/eLife.30094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821459/
https://www.ncbi.nlm.nih.gov/pubmed/29309035
http://dx.doi.org/10.7554/eLife.30094

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