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Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer

The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in postmenopausal women with estrogen receptor-posit...

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Detalles Bibliográficos
Autores principales: Durairaj, Chandrasekar, Ruiz-Garcia, Ana, Gauthier, Eric R., Huang, Xin, Lu, Dongrui R., Hoffman, Justin T., Finn, Richard S., Joy, Anil A., Ettl, Johannes, Rugo, Hope S., Zheng, Jenny, Wilner, Keith D., Wang, Diane D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821476/
https://www.ncbi.nlm.nih.gov/pubmed/29360661
http://dx.doi.org/10.1097/CAD.0000000000000589