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Long-term Administration of Salicylate-induced Changes in BDNF Expression and CREB Phosphorylation in the Auditory Cortex of Rats

We investigated whether salicylate induces tinnitus through alteration of the expression levels of brain-derived neurotrophic factor (BDNF), proBDNF, tyrosine kinase receptor B (TrkB), cAMP-responsive element-binding protein (CREB), and phosphorylated CREB (p-CREB) in the auditory cortex (AC). BACKG...

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Detalles Bibliográficos
Autores principales: Yi, Bin, Wu, Cong, Shi, Runjie, Han, Kun, Sheng, Haibin, Li, Bei, Mei, Ling, Wang, Xueling, Huang, Zhiwu, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821486/
https://www.ncbi.nlm.nih.gov/pubmed/29342042
http://dx.doi.org/10.1097/MAO.0000000000001717