The novel dithiocarbamate, DpdtC suppresses HER2-overexpressed cancer cells by up-regulating NDRG1 via inactivation of HER2-ERK 1/2 signaling

Dithiocarbamate has been tested for its effective anti-tumor activity, but the underlying mechanism remains unclear. We previously prepared a novel diththiocarbamate derivative, DpdtC with an ability of catalase inhibition. Here, we for the first time investigated the growth inhibition effects of Dp...

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Detalles Bibliográficos
Autores principales: Yang, Yun, Liu, Youxun, Guo, Rui, Fu, Yun, Zhang, Ziheng, Zhang, Pengfei, Zhou, Pingxin, Wang, Tingting, Huang, Tengfei, Li, Xiaotong, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821706/
https://www.ncbi.nlm.nih.gov/pubmed/29467385
http://dx.doi.org/10.1038/s41598-018-21768-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821706/
https://www.ncbi.nlm.nih.gov/pubmed/29467385
http://dx.doi.org/10.1038/s41598-018-21768-1

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