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A Genetic Screen for Investigating the Human Lysosomal CystineTransporter, Cystinosin
Cystinosin, a lysosomal transporter is involved in the efflux of cystine from the lysosome to the cytosol. Mutations in the human cystinosin gene (CTNS) cause cystinosis, a recessive autosomal disorder. Studies on cystinosin have been limited by the absence of a robust genetic screen. In the present...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821828/ https://www.ncbi.nlm.nih.gov/pubmed/29467429 http://dx.doi.org/10.1038/s41598-018-21483-x |