Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4

Semaphorin-4A (Sema4A) has been implicated in the co-stimulation of T cells and drives Th1 immune responses by binding to the receptor T-cell immunoglobulin and mucin domain protein 2 (Tim-2) in mice. Here we show that human, but not murine, Sema4A is preferentially expressed on antigen-presenting c...

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Detalles Bibliográficos
Autores principales: Lu, Ning, Li, Ying, Zhang, Zhiqiang, Xing, Junji, Sun, Ying, Yao, Sheng, Chen, Lieping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821868/
https://www.ncbi.nlm.nih.gov/pubmed/29467366
http://dx.doi.org/10.1038/s41467-018-03128-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821868/
https://www.ncbi.nlm.nih.gov/pubmed/29467366
http://dx.doi.org/10.1038/s41467-018-03128-9

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