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Hematopoietic stem/progenitor cell senescence is associated with altered expression profiles of cellular memory-involved gene
To evaluate the contributions of cellular memory mechanisms to hematopoietic stem/progenitor cell (HSPC) senescence. HSPCs (Lin(−)CD117(+), hereafter referred to as HSPC) were separated from young (6-week-old) and aged (18-month-old) mice using Magnetic Activated Cell Sorting (MACS). Cell cycle dist...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821940/ https://www.ncbi.nlm.nih.gov/pubmed/29363553 http://dx.doi.org/10.1042/BSR20171589 |