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Hematopoietic stem/progenitor cell senescence is associated with altered expression profiles of cellular memory-involved gene

To evaluate the contributions of cellular memory mechanisms to hematopoietic stem/progenitor cell (HSPC) senescence. HSPCs (Lin(−)CD117(+), hereafter referred to as HSPC) were separated from young (6-week-old) and aged (18-month-old) mice using Magnetic Activated Cell Sorting (MACS). Cell cycle dist...

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Detalles Bibliográficos
Autores principales:	Dong, Yongpin, Lian, Xiaolan, Xu, Yanwu, Hu, Haiyan, Chang, Cen, Zhang, Haiyin, Zhang, Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821940/ https://www.ncbi.nlm.nih.gov/pubmed/29363553 http://dx.doi.org/10.1042/BSR20171589

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