Cargando…

Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis. Fluconazole resistance in this yeast is almost exclusively due to activating mutations in the transcription factor Pdr1...

Descripción completa

Detalles Bibliográficos
Autores principales: Whaley, Sarah G., Caudle, Kelly E., Simonicova, Lucia, Zhang, Qing, Moye-Rowley, W. Scott, Rogers, P. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821985/
https://www.ncbi.nlm.nih.gov/pubmed/29507891
http://dx.doi.org/10.1128/mSphere.00466-17