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Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata
The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis. Fluconazole resistance in this yeast is almost exclusively due to activating mutations in the transcription factor Pdr1...
Autores principales: | Whaley, Sarah G., Caudle, Kelly E., Simonicova, Lucia, Zhang, Qing, Moye-Rowley, W. Scott, Rogers, P. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821985/ https://www.ncbi.nlm.nih.gov/pubmed/29507891 http://dx.doi.org/10.1128/mSphere.00466-17 |
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