Cargando…

GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons

Human mutations of the GRID1 gene encoding the orphan delta1 glutamate receptor-channel (GluD1) are associated with schizophrenia but the explicit role of GluD1 in brain circuits is unknown. Based on the known function of its paralog GluD2 in cerebellum, we searched for a role of GluD1 in slow gluta...

Descripción completa

Detalles Bibliográficos
Autores principales: Benamer, N, Marti, F, Lujan, R, Hepp, R, Aubier, T G, Dupin, A A M, Frébourg, G, Pons, S, Maskos, U, Faure, P, Hay, Y A, Lambolez, B, Tricoire, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822454/
https://www.ncbi.nlm.nih.gov/pubmed/28696429
http://dx.doi.org/10.1038/mp.2017.137